Pharmacognosy Faculty

Awards and Recognitions:

Awarded Doctorate from Andhra University, Visakhapatnam in 2015.

Fields of Specialization:

Isolation, Separation and Characterization of Natural molecules.
Formulation & Evaluation of Polyherbal products.
Pharmacological screening of Natural molecules
Nutraceutical formulations

Research Papers Published:

• SVVNSM Lakshmi, K. Rama Devi, G. Shravani, S. Pavani, S. Nikhitha. Systematic review on phytochemical profile and pharmacology of a mangrove shrub, Scyphiphora hydrophyllacea C.F. Gaertn. Annals of Phytomedicine 2024; 13(1): 417-430. DOI:10.54085/ap.2024.13.1.42
• SVVNSM Lakshmi, Durga Bhavani Penmetsa, Kondal Reddy Yennam, Sadasivaiah Byalla. FTIR Analysis, Total Phenolic Content, Antioxidant and Antidiabetic activities of Hildegardia populifolia (Roxb.) Schott and Endl. (Malvaceae). Pharmacognosy Research 2025; 17(2): 679-688. DOI:10.5530/pres.20252113
• SVVNSM Lakshmi, Kukati L, Rahman A, Fatima A, Menon V. Design, Development and Optimization of Gastro-retentive floating in-situ gels loaded with Carvedilol microspheres using response surface methodology. Acta Marisiensis - Seria Medica 2025; 71(1): 60-72. DOI: https://doi.org/10.2478/amma-2025-0011
• S.Ganapaty, B.N.Mallika, S.Balaji, SVVNSM Lakshmi, P.S.Thomas, K.V.Ramana. A review of Phytochemical studies of Digitalis Species. Journal of Natural Remedies, 3 (2003) 106-128.
• Pattari Lohitha, K.Ramanjaneyulu, SVVNSM Lakshmi, P.Rajavarma Buddaraj, M.Usha Kiran, Pavani.  Invitro Evaluation of Anti Microbial Activity of Butea monosperma (L) Leaf Hexane: Ethanol (1:1) Extract. International  Journal of  Drug Development & Research. 3 (2011) 267-272.
  
• K.Ramanjaneyulu, SVVNSM Lakshmi, K.M.Devraj K.Narendar Reddy. Evaluation of Papain Immobilization in Chitosan Nanoparticles using different cross linking agents.  Journal of Pharmacy Research, 4 (2011).
  
• Kondal Reddy.Y, Appaji.D, KVM Krishna, Lakshmi SVVNSM Purification, Characterization & Quantification of type II Class CGMP-Dependent Protein Kinase II (pkg-II), from rat intestinal mucosa.1633-1641, World Journal of Pharmacy and Pharmaceutical Sciences, 4 (2015) 1633-1641.
  
• KVM Krishna, Lakshmi SVVNSM, Alluri Ramesh, Rajendra Prasad. Management of Pharmaceutical Wastage. Asian Journal of Pharmaceutical Research, 3 (2015) 51-56.
  
• Amareswar S, Prasanthi Y, Viswanadham, SVVNSM Lakshmi. Formulation of in vitro evaluation of Floating tablets of Piretanide.  World Journal of Pharmacy and Pharmaceutical Sciences, 6 (2017) 1054-1066.
  
• SVVNSM Lakshmi, A Siva Mallikarjuna Reddy, S Ganapaty, B Ganga Rao, A Ramesh. Anti cataract potential of Boerhavia diffusa roots on galactose induced cataractogenesis. Indian Journal of Experimental Biology, 55 (2017) 838-844.
  
•  Ramesh Babu, V., Rangaswamy, S., Lakshmi, S., Musuluri, M., Mak, K. K., Syed, T. Abbaraju, V. D. N. K. (2024). Design, Synthesis, Anticancer Evaluation and Molecular Docking Studies of Amide Derivatives of Thienopyrimidine Isoxazoles. Organic Preparations and Procedures International, 1–12. https://doi.org/10.1080/00304948.2024.2316449
  
• Lakshmi, S. V. V. N. S. M., Chandrika, M., Nandin, R., Pavithra, M. N., Korni, R., Ahsan, M. J. (2024). An Insight into the Traditional Uses, Phytoconstituents and Pharmacological Activities of the Genus Tylophora. Research Journal of Pharmacognosy, 11(1): 71-108. doi: 10.22127/rjp.2023.395934.2112
• Ahsan, M.J.; Gautam, K.; Ali, A.; Ali, A.; Altamimi, A.S.A.; Salahuddin; Alossaimi, M.A.; Lakshmi, S.V.V.N.S.M.; Ahsan, M.F. (2023). Synthesis, Anticancer Activity, and In Silico Studies of 5-(3-Bromophenyl)-N-aryl-4H-1,2,4-triazol-3-amine Analogs. Molecules, 28, 6936. https://doi.org/10.3390/molecules28196936
• Gugulothu, S. ., Rhoda, B. ., Pulipati, S. ., Lakshmi, S. ., Rhoda, B. ., Varsha, G., Varma, K.., & Latha, G. (2023). Development of Controlled Release Osmotic Drug Formulation by Using Proponolol Hydrochloride to Improve Bioavailability. Journal of Coastal Life Medicine, 11(1), 49–63.
• Sreeharsha, N.; Prasanthi, S.; Mahalakshmi, S.V.V.N.S.; Goudanavar, P.S.; Naveen, N.R.; Gowthami, B.; Fattepur, S.; Meravanige, G.; Asdaq, S.M.B.; Anwer, M.K.; et al. (2022). Enhancement of Anti-Tumoral Properties of Paclitaxel Nano-Crystals by Conjugation of Folic Acid to Pluronic F127: Formulation Optimization, In Vitro and In Vivo Study. Molecules, 27, 7914. https://doi.org/10.3390/molecules27227914.
• S. V. V. N. S. M. Lakshmi, G. Suryam, Faheemuddin MD, B. Lakshmi Satya, M. Naga Pavithra, A. V. Rama Raju. (2022). Herbomineral Toothpaste: A Novel Formulation for Dental Caries – An In Vitro Study. Asian Journal of Pharmaceutics, 16(3):278
• Lakshmi, S.V.V.N.S.M. Reddy, A. Siva Mallikarjuna, Vidya, S. (2019). Pharmacological screening of aqueous extract of Sesbania grandiflora for anti-glaucomic activity in Rabbits. Indian journal of natural products and resources, 10(1):43-47

BOOKS:

 A text book of Pharmacognosy and Phytochemistry-I in the year 2023 by Rubicon Publications.

Awards and Recognitions:

• InSc Young researcher award 2020 by Institute of Scholars in 2020.
• Third prize in Herb photo contest-2020 with Title “Ayurveda for Covid 19 pandemic” organized by Hindu College of Pharmacy.
• Best oral presentation at “START HERB: Journey from Innovation to Entrepreneurship in Herbals” organized by D.Y. Patil Deemed to be University,School of Pharmacy, Navi Mumbai and Association of Pharmaceutical Research (APR) held on 14th & 15th October 2022.
• Sakura Science Fellowship, Japan Science and Technology Agency (Saga University, 2–12 September 2024).
• First Prize in Video Making, Women’s Day Celebrations, APTI and JNTUH.
• Best Oral Presentation, START HERB 2022, D.Y. Patil University & APR.
• Third Prize, Herb Photo Contest 2020 – Ayurveda for COVID-19 Pandemic, Hindu College of Pharmacy.
• InSc Young Researcher Award, 2020, Institute of Scholars.
• Best Poster Award, 12th Annual National ISP Convention, ISF College of Pharmacy, Moga, Punjab, 2009.

Fields of Specialization:

Fields of Specialization:
Herbal medicines and herbal supplements
Herbal formulations
Neuroprotective drug

Research Papers Published:

1.    Santhosha D, A new herbal initiative for Vitiligo therapy, Indian drugs,46(6), 2009, 5-10
2.    D.Santhosha, Effect of UV radiation in the antivitiligo activity therapy by Piperine topical formulation, Scholars research library, Archives of applied science, 2(4), 2010, 165-169.
3.    Santhosha D, Formulation and evaluation of Piperine cream-A new Herbal dimensional approach for Vitiligo patients, International journal of pharmacy and pharmaceutical sciences,3(2),2011,29-33.
4.    Santhosha D, Development of a herbal topical formulation for Vitiligo, Indian drugs, 47(12), 2010, 17-21.
5.    Santhosha D, Respirocytes-A new generation of Nanorobots, Pharma buzz, 5(8), 2010, 38-40.
6.    D.Santhosha, Ethno medicinal practices of Plants in Nalgonda district, Andhra Pradesh, India: A Traditional survey, Inventi rapid: Ethanopharmacology, 2(2), 2011, 3-6.
7.    Santhosha D, Medicinal plants used by the ethnic practitioners in Nalgonda district, Andhra Pradesh, India, International journal of research in Ayurveda and Pharmacy,1(2),2010,493-496.
8.    Santhosha Dasarapu, Anti-diabetic activity of Bambusa arundinaceae seed extracts on Alloxan induces diabetic rats, International journal of pharmaceutical research and development, 3(5), 2011, 83-86.
9.    Santhosha D, Formulation and evaluation of Rosiglitazone mouth dissolving tablets, International journal of Pharma and biosciences,1 (1)2010, 1-9.
10.    D.Santhosha, Punarnava- A Review, Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2 (4), 2011, 427-436.
11.    D.Santhosha, Phytochemical screening and anti-oxidant activity of ethanolic extract of Heliotropium indicum .International journal of pharmacy,6(8),2015,567-572.
12.    D.Santhosha, Pharmacological study for investigation of antihelmintic activity of Cleome Gynandra against adult indian earthworm pheritima posthuma,  Indo american journal of pharmaceutical research, 2015, vol 5, issue 10, 2015.
13.    D.Santhosha, Evaluation of Antidiarrhoeal Activity Cleome gynandra Leaf Extracts on Magnesium Sulphate- and Castor Oil-Induced Diarrhoea in Wistar Rat. January 2015, DOI: 10.5958/2321-5836.2015.00037.3.
14.    D.Santhosha, Evaluation of Antiulcer Activity of Polyherbal Formulation Against Ethanol Induced Gastric Ulcer In Albino Rats, International Journal of Innovation Sciences and Research,Vol.5, No, 06, pp. 761-765, 2016
15.    Dasarapu Santhosha, ,Alluri Ramesh, Emandi ,Hemalatha, Malothu Nagulu,Neuroprotective effect of ethanolic extract of Heliotropium indicum against transient global ischemia induced brain damage in rats,   IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS), Volume 11, Issue 5 Ver. III (Sep. - Oct.2016), PP 06-11.
16.    Dasarapu Santhosha, Investigation of phytochemical screening and in-vitro anthelminthic activity of Zaleya decandra IJPPR, Vol 7 Issue 3,Oct 2016.
17.    Dasarapu Santhosha, Malothu Nagulu, Emandi Hemalatha, Alluri Ramesh ,A Review on Heliotropium indicum,European journal of Biomedical  and Pharmaceutical sciences,  EJBPS, 2018, Volume 5, Issue 10, 182-193.
18.    D. Santhosha,Pharmacognostic Study, Phytochemical Screening and Neuroprotective, Activity of Methanolic extract of Gynandropsis gynandra against Transient, Global Ischemia induced brain damage in rats, Vol. 09 |Issue 03|July-September | 2019 AJPSci. 
19.D.Santhosha, Review on pharmacological activities of Mangifera indica and Zingiber officinale,  Journal of Pharmacognosy and Phytochemistry 2020; 9(3): 1166-1170.
20. Dr.D.Santhosha,Dineshmohan.S,S.Lakshmi,Gupta VRM,Sudha, Pharmaceutical co-crystals of eprosartanmesylate:Formulation,characterization and evaluation,International journal of pharmaceutical research,July-Sept 2021,Vol 13 issue 3,pg no 1018-1021.
21. Dasarapu Santhosha (2022). Pharmacognosy, phytochemistry and pharmacological profile of Gmelina asiatica:A review. Ann. Phytomed., 11(2):205-213. http://dx.doi.org/10.54085/ap.2022.11.2.22.

22.        Swamikannu DM, Santhosha D. The gut-liver nexus: Exploring gut microbiota dysbiosis in non-alcoholic fatty liver disease and its therapeutic implications. Egypt Liver J. 2024;14:28. (Scopus)

23.       Santhosha D*, Swamikkannu DM. Pharmacognosy, phytochemistry, and pharmacological profile of Gynandropsis gynandra L.: A review. Ann Phytomed. 2023;12(2):1–9. (WoS)

24.      Santhosha D*, Alluri R. Pharmacognosy, phytochemistry, and pharmacological profile of Gmelina asiatica L.: A review. Ann Phytomed. 2022;11(2):205–213. (WoS)

25.       Dinesh Mohan S, Santhosha D, Lakshmi SVVNSM, Gupta VRM, Sudha T. Pharmaceutical co-crystals of eprosartan mesylate: Formulation, characterization, and evaluation. Int J Pharm Res. 2021;13(3):1018–1021. (Scopus)

26.       Dinesh Mohan S, Santhosha D, Gupta VRM, Mrunalini S. The outbreak of novel coronavirus: Genesis, detection, treatment, and management. Coronavirus. 2021;2(3):313–324. (WoS)

27.       Jahnavi CH, Jyothsna K, Lakshmi Geetika D, Shrutha Keerthi G, Santhosha D, Ramesh A. Review on pharmacological activities of Mangifera indica and Zingiber officinale. J Pharmacogn Phytochem. 2020;9(3):1166–1170. (Scopus)

 28.      Santhosha D*. Pharmacognostic study and neuroprotective activity of Gynandropsis gynandra against transient global ischemia-induced brain damage in rats. Asian J Res Pharm Sci. 2019;9(3):1–6.

29.       Santhosha D*, Ramesh A, Hemalatha E, Nagulu M. Neuroprotective effect of ethanolic extract of Heliotropium indicum against transient global ischemia-induced brain damage in rats. IOSR J Pharm Biol Sci. 2016;11(5):6–11.

 30.      Santhosha D*, Ramesh A, Hemalatha E, Nagulu M. Phytochemical screening and antioxidant activity of ethanolic extract of Heliotropium indicum. Int J Pharm. 2015;6(8):567–572. (Scopus)

31.    Santhosha D, Ramesh A, Sravan Prasad M, Sathis Kumar D, Pawan Kumar B, Dhanalakshmi CH. Punarnava: A review. Res J Pharm Biol Chem Sci. 2011;2(4):427–436.

32.     Sravan Prasad M, Venkateshwarlu G, Santhosha D, Ravinder Nath A. Anti-diabetic activity of Bambusa arundinaceae seed extracts on alloxan-induced diabetic rats. Int J Pharm Res Dev. 2011;3(5):83–86.

33.    Vinod KR, Anbazhagan S, Santhosha D. A new herbal dimensional approach for vitiligo patients. Int J Pharm Pharm Sci. 2011;3(Suppl 2):1–5. (Scopus)

34.     Sravan Prasad M, Rao KNV, Santhosha D, Vijaya Bhaskar K, Suresh Kumar P, Sathis Kumar D, Chaitanya RSNAKK, Srikanth Goud CH. Ethnomedicinal practices of plants in Nalgonda District, Andhra Pradesh, India: A traditional survey. Inventi Rapid Ethnopharmacol. 2011;2(2):3–6.

35.     Sravan Prasad M, Rao KNV, Santhosha D, Vijaya Bhaskar K, Suresh Kumar P, Sathis Kumar D, Chaitanya RSNAKK, Srikanth Goud CH. Medicinal plants used by the ethnic practitioners in Nalgonda District, Andhra Pradesh, India. Int J Res Ayurveda Pharm. 2010;1(2):493–496.

 36.   Arjun G, Sravan Prasad M, Santhosha D, Achaiah G. Formulation and evaluation of rosiglitazone mouth-dissolving tablets. Int J Pharma Biosci. 2010;1(1):1–9.

 37.     Vinod KR, Banji D, Banji O, Sandhya S, Santhosha D. Respirocytes: A new generation of nanorobots. Pharma Buzz. 2010;5(8):38–40.

38.    Vinod KR, Anbazhagan S, Santhosha D, Banji O, Banji D, Sandhya S. Effect of UV radiation in the antivitiligo therapy by piperine topical formulation. Arch Appl Sci Res. 2010;2(4):165–169.

39.    Vinod KR, Anbazhagan S, Sandhya S, Banji D, Santhosha D. Development of a herbal topical formulation for vitiligo. Indian Drugs. 2010;47(12):17–21.

40.    Vinod KR, Santhosha D, Anbazhagan S. A new herbal initiative for vitiligo therapy. Indian Drugs. 2009;46(6):5–10.

BOOKS:

1“Formulation and evaluation of chickpeas cream” published by Lambert publishing house with ISSN number 978-3-659-37074-8.
2. Evaluation of anti-pyretic and analgesic activity of Chloris barbata published in Lambert publishing house with ISSN number  978-3-659-74199-9.
3. Book of forensic pharmacy for Dr.Reddy’s Laboratories for BSc students under Dr.B.R.Ambedkar University.
4. Cyanobacteria as potential bioresources for multifaceted sustainable utilization: published as book chapter in New and future developments in microbial biotechnology and bioengineering with ELSEVIER Publishing house with page number 23-37.https://doi.org/10.1016/B978-323-85579-2.00020-4
 5. D. Santhosha and S. Dinesh mohan (2023). Pharmacognosy, phytochemistry and pharmacological profile of Gynandropsis gynandra L.: A review. Ann. Phytomed., 12(2):1-9. http://dx.doi.org/10.54085/ap.2023.12.2.90.
6.Swamikkannu, D.M., Dasarapu, S., Siva, R.V. et al. The gut-liver nexus: exploring gut microbiota dysbiosis in non-alcoholic fatty liver disease and its therapeutic implications. Egypt Liver Journal 14, 28 (2024). https://doi.org/10.1186/s43066-024-00331-w
7.D. Santhosha, S. Dineshmohan, M. Chandrika, E. Rupika and A. Ramesh (2023). Beyond the basics: A comprehensive review of the thyroid gland and its ailments. J. Phytonanotech. Pharmaceut. Sci., 3(4):1-5. http://dx.doi.org/10.54085/ jpps.2023.3.4.3
8.S. Dinesh Mohan D. Santhosha , V.R.M. Gupta and S. Mrunalini The Outbreak of Novel Coronavirus-a New Type of Threat in 2020: Genesis, Detection, Treatment, and Management Coronaviruses, 2021, 2, 313-324 DOI: 10.2174/2666796701999200905093719.
9.Santhosha D, Ramesh A, Kondi V, Dineshmohan S, Arifa Begum S. Role of nutraceuticals in healthcare and rural economy. In: Bioresource Processing: Technologies and Applications. Frontiers in Life Sciences [FDP Compendium]. 2025. p. 183–212.
10. Santhosha D*, Kondi V, Dineshmohan S, Mavulati SC, Tiwari ON. Harnessing nanopolysaccharides for sustainable agriculture and environmental protection. In: Soil Algae. Springer, Singapore; 2025. p. 267–287. DOI: 10.1007/978-981-97-9873-5_12.
11.Kondi V, Sabbania V, Alluri R, Sunil Kumar T, Chawla P, Santhosha D, Tiwari ON. Cyanobacteria as potential bioresources. In: Gupta VK, editor. New and Future Developments in Microbial Biotechnology and Bioengineering: Cyanobacteria Biotechnology. Elsevier; 2021. p. 23–37. DOI: 10.1016/B978-323-85579-2.00020-4.
12.Santhosha D*, Alluri R. Evaluation of anti-pyretic and analgesic activity of Chloris barbata. Lambert Academic Publishing; 2015. ISBN: 978-3-659-74199-9.
13. Santhosha D*, Alluri R. Formulation and evaluation of chickpeas cream. Lambert Academic Publishing; 2013. ISBN: 978-3-659-37074-8.
  

Student Projects
 1.D. Santhosha, S. Dineshmohan, M. Chandrika, E. Rupika and A. Ramesh (2023). Beyond the basics: A comprehensive review of the thyroid gland and its ailments. J. Phytonanotech. Pharmaceut. Sci., 3(4):1-5. http://dx.doi.org/10.54085/ jpps.2023.3.4.3

Professional Memberships

• Lifetime Member, Indian Pharmaceutical Association (ID: TS/NS/ON/LM/000032).
• Lifetime Member, APTI (ID: TL/LM-994).
• Lifetime Member, Institute of Scholars (ID: InSc20203068).
• Member, Association of Pharmaceutical Research (2022–2023).

Awards and Recognitions:

Best Oral Presentation Award at an inter-departmental Conference of NHRI Research Day, Taiwan, 2022.
Research Ethics Certification from Academic Research Ethics Education (AREE),Taiwan, 2022.
Best Poster Award at NIPER-CDRI (Central Drug Research Institute) Joint Symposium, Lucknow, INDIA, 2012.

Fields of Specialization:

1. Doctoral Research : Mitochondrial Lon drives Cisplatin Resistance by regulating Calcium Signaling in Oral Cancer”
2. Cell culture techniques
3. Molecular biology: qPCR, RT-PCR, RNA and DNA extraction, Transfection.
4. Protein chemistry: Expertise on Protein purification (Affinity chromatography), Protein/DNA Gel electrophoresis (SDS-PAGE),Western blotting, ELISA, Intracellular staining, Co-immunoprecipitation, Immunofluorescence, Organelle fractionation, Immunohistochemistry (IHC).
5. Instrumentation: FACS, Confocal microscope, Fluorescence microscope, Live imaging microscope, Intracellular Ca+2 imaging.
6. Analytical Methods: Column, Thin layer, Ion Exchange, Gel and Paper Chromatography, HPLC
7. Cancer assays: Cell cytotoxicity, Angiogenesis, Colony formation and Wound healing assays.
8. Clinical: Patient tissue sample collection, staining and analysis.
9. Designing of xenograft experiments in mice

Research Papers Published:

1. Main author. “Lon up regulation contributes to cisplatin resistance by triggering NCLX-mediated mitochondrial Ca2+release in cancer cells” Cell Death and Disease (2022). (IF - 9.2)
2. Co–author. “Lon-dependent ULK1-FUNDC1 activity promotes mitophagy at the ER-mitochondria contact under hypoxia)”. Cell Death and Disease (2023). (IF - 9.2)
3. Co–author. “Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: Foe or Friend?” Journal of Biomedical Science (2022). Review. (IF - 10.9)

BOOKS: 

Book Chapter on : Advanced Bio-Physical Techniques in Bio-Sciences , Springer Nature 2025: DOI No:10.1007/978-3-031-94551-9

Awards and Recognitions:

Fields of Specialization:

1). Multiple Integrals
2). Differential Equations
3). Theory of Matrices

Research Papers Published:

BOOKS: